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In addition, reactive astrocytes at the perimeter of the fibrotic scar proliferate to form perilesional barrier that protects the adjacent viable nervous tissue

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The latter experimental setup resembles the situation of humans affected by NF2 disease, where one copy of the Nf2 gene is lost in the entire body due to a germline mutation [30]

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Basic Clin Pharmacol Toxicol 123:6271

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