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However, Xc-system inhibition results in glutathione and Cys deficiencies, triggering ferroptosis (Li F

Furthermore, oxidative stress can impede the nucleoplasmic translocation of pancreaticoduodenal homeobox factor 1 (PDX-1), impair energy metabolism, and reduce insulin production and release (Duni et al., 2019)

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1.06, p = 0.03) (Figure 1E), and in the AD group (1.11 vs