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Patients often experience shoulder pain during overhead activities, weakness in lifting or rotating the arm, and stiffness that may worsen at night
Most of these substances do not have an immediate effect after a single administration and must be used for some length of time before there is a measurable improvement
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The peroxidation of cell membrane lipids, triggered by iron and the inactivation of antioxidant pathways, results in the accumulation of lipid peroxides and reactive oxygen species (ROS), causing cell membrane rupture and cell death
