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Same goes for MOTS-C, which is currently in an ongoing Phase 2a clinical trial evaluating its effects on insulin sensitivity in adults with prediabetes and obesity

The salt form does not change what the peptide does once it reaches target tissues

However, a recent human clinical trial has provided new insights into its potential benefits for chronic pain management

Medication Interactions Certain medications reduce the absorption of methylcobalamin, cyanocobalamin, and other B12 supplements, including: Proton pump inhibitors (omeprazole, esomeprazole, and lansoprazole) H2-receptor antagonists (cimetidine, famotidine, and ranitidine) Metformin Colchicine Cholestyramine Certain antibiotics (neomycin and chloramphenicol) If you use these or other medications, talk with a healthcare provider about ways to maintain healthy levels of B12.