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Of these enzymes, CD38, PARPs and SARM1 appear to significantly contribute to cellular NAD degradation [1-4, 6, 19, 28, 34-39]

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B12 supplements may improve heart health by reducing homocysteine levels, a compound that is associated with an increased risk of heart disease

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The Thiamine deficiency results in lesions on the brain that can cause confusion, short term memory loss, ataxia, and other unpleasant symptoms

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However, taking extremely high doses may cause acne, rashes, or place stress on the kidneys in certain cases

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