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19 Fever, rash, facial edema, eosinophilia DRESS often starts with fever and a rash, characterized as a nonspecific severe pruritic skin eruption affecting more than 50% of the body surface area

doi: 10.1016/j.numecd.2018.07.002 98 AkdoanMTamerMNCreECreMCKroluBKDelibaN

Importantly, immune reaction is a hallmark of pathologic CNS that plays essential roles in tissue injury and repair (Eyo and Dailey, 2013
