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There is a need for personalized treatment/mechanism-based approaches for DPN, which includes the targeted interventions based on the comorbid risk factors and underlying disease mechanisms specific to each patient, besides the optimal diabetes treatment ALA is an effective first-line disease-modifying antioxidant therapy for long-term management of DPN

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Dihydroartemisinin enhances the inhibitory effect of sorafenib on HepG2 cells by inducing ferroptosis and inhibiting energy metabolism