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Description
Characteristic appearances are visible on MRI and include white matter hyperintensities, which are present in many middle aged and older individuals, and predict future stroke and dementia risk

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Curcumin downregulates the phosphoinositide-3-kinase/AKT/mechanistic target of rapamycin (PI3K/AKT/mTOR) pathway, inhibiting head and neck cancer cell growth and progression

Individual responses, safety profiles and pharmacokinetic parameters can vary significantly between species and between in vitro and in vivo models
