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1a), 25 to 40 mg of both proteins were routinely obtained from a 600 ml culture of Hi5 cells

doi: 10.3892/ijmm.2018.3879

Chlorogenic acid, a natural polyphenol, potentiated the apoptotic effect of Regorafenib in human hepatocellular carcinoma cells by the inhibition of anti-apoptotic Bcl2, Bcl-xL, MAPK and PI3K/Akt/mTOR pathway and activation of pro-apoptotic Bax and Caspase 3/7 [269]