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Quality by design approach for the development of self-emulsifying systems for oral delivery of febuxostat: pharmacokinetic and pharmacodynamic evaluation

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Biomedical Materials & Devices 2026 , 31 Karen Khachatryan, Oskar Michalski, Klaudia Michalska

A2A receptor activation upregulates vascular endothelial growth factor (VEGF), promotes angiogenesis in dermal microvasculature, stimulates fibroblast migration and proliferation, and suppresses inflammatory cytokine release
