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Call your vet if your cat has persistent vomiting or diarrhea, stops eating, seems unusually weak, or shows breathing changes

[161] Behavioral treatments A 2018 systematic review and network meta-analysis of 50 trials involving 12 different psychosocial interventions for amphetamine, methamphetamine, or cocaine addiction found that combination therapy with both contingency management and community reinforcement approach had the highest efficacy (i.e., abstinence rate) and acceptability (i.e., lowest dropout rate)

Previous metabolomic studies have highlighted disruptions in the TCA cycle, amino acid metabolism, and lipid metabolism during drug exposure, withdrawal, and re-exposure using rodent urine and serum following intraperitoneal (i.p.) injection of morphine 5 and heroin 5,6