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Vitamin B 6 (pyridoxine) is a cofactor involved in carbohydrate, fat, and amino acid metabolism [29]

In vitro , they found that NNMT knockdown significantly lowers hepatocyte glucose output (50%) and that NNMT overexpression significantly increases hepatocyte glucose output (1.4-fold) [14]

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Under the optimal cut-off value, the models sensitivity was 92.6% (50/54) and the specificity was 93.7% (44/47), and the average accuracy based on 100 cross validations was 88.9% ( Figure 4 )