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In Clinical Trials In Treatment-Naive Subjects In a pooled analysis of antiretroviral-naive subjects receiving GENVOYA in Studies 104 and 111, genotyping was performed on plasma HIV-1 isolates from all subjects with HIV-1 RNA greater than 400 copies per mL at confirmed virologic failure, at Week 144, or at time of early study drug discontinuation

In our experiment, MDA levels increased and levels of the antioxidant SOD decreased in the testis tissue in group B, indicating that the production and removal of oxygen-free radicals in the testis tissue of rats in a simulated high-altitude environment were unbalanced

Cuccurazzu B, et al

Downregulation of BDNF mRNA in the hippocampal dentate gyrus after re-exposure to cues previously associated with footshock