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They can activate repair processes that protect DNA and assist in repairing damage
By disrupting the binding of FOXO4 to the p53 proteina key regulator of cell deaththis peptide allows senescent cells to self-destruct safely, preventing damage to surrounding tissue
Cell Tissue Res 368:371378
CHIP stabilizes amyloid precursor protein via proteasomal degradation and p53-mediated trans-repression of -secretase
