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Description
DES (1-3) IGF-1 DES IGF-1 is a truncated form of IGF-1 with high muscle tissue affinity and localized growth effects
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The interest traces to a 2014 Nature paper showing that knocking down NNMT in fat and liver protected mice against diet-induced obesity, glucose intolerance, and fatty liver, partly by shifting adipose NAD+ and SAM levels [4]
