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Moreover, supplementation of glutathione is not ideal because it is not transported inside the cells, indeed, it needs to be synthesized within them

In addition, betaine can also be synthesized de novo from dietary choline in the mammalian liver and kidney via a two-step enzymatic process in which choline is first oxidized to betaine aldehyde by choline dehydrogenase
& Seikai, T

22nd July 2015