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329 This leads to the inhibition of effector T cell and NK cell functions while promoting Treg differentiation, thus impairing antitumor immunity 330 (Fig

m , Intensity of MitoSOX was normalized to number of nuclei (Hoechst) and expressed as fold change from GFP control (n=3)

Nrf2 agonists that have made progress in mouse disease models: Oleanolic acid derivatives CDDO-Me and CDDO-Im, 15d-PGJ 2 [15-deoxy-Delta (12,14)-prostaglandin J (2)], oltipraz, fumarate, triterpenoids (such as bardoxolone methyl, BARD) and sulforaphane (SFN), etc (Yamamoto et al., 2018

Lower H 2 S production has been associated with myocardial ischaemia, angina and cardiovascular disease (Polhemus et al ., 2014)
