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This mutation leads to detrimental phenotypes such as premature aging, senescence, immune deficiency, and neurodegeneration 111,288
Proc Natl Acad Sci U S A 87(14):53685372 Dolan ME, Roy SK, Fasanmade AA, Paras PR, Schilsky RL, Ratain MJ (1998) O 6 -benzylguanine in humans: metabolic, pharmacokinetic, and pharmacodynamic findings
Abstract Background Intracellular hydroperoxides are harmful reactive oxygen species that can cause damage
Synbiotics leverage the complementary effects of probiotics and prebiotics, enhancing colonization resistance, SCFA production, and immunomodulation
