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J Lipid Res 58(3):519528 Carnevale R, Nocella C, Petrozza V, Cammisotto V, Pacini L, Sorrentino V et al (2018) Localization of lipopolysaccharide from Escherichia Coli into human atherosclerotic plaque
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Due to its high lipophilicity, it may accumulate in adipose tissue when used chronically [4,66]
Conversely, impaired CREB signaling, as seen in chronic stress, oxidative injury, or sleep disruption, may exacerbate immune dysregulation and reduce neurotrophic support
