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Previous studies have shown that, under certain circumstances, such as the induction of ER stress or blockade of ER-to-Golgi transport, the ER core-glycosylated form of CFTR, including the F508 mutant, can be transported to the cell membrane via the UPS pathway, bypassing the Golgi apparatus 12,13,14,15

A primary role for cyclic ADP-ribose in hypoxic pulmonary vasoconstriction

For something to be added to the WADA Prohibited List, it must meet two of the three inclusion criteria: 1) it has the potential to enhance performance 2) it poses a health risk to athletes and 3) it violates the spirit of sport

PMID 17606868