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This change is particularly relevant as although Firmicutes is recognized as being composed of fiber fermenting species and usually predominant in the caeca of chickens [54, 55], Actinobacteria members have been proposed as probiotic, especially useful in poultry farming due to their role in short chain fatty acid production [56]

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Discard any vial that looks turbid or contains floating debris both indicate protein aggregation or contamination

, Helicobacter pylori , Lactobacillus spp