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Additional longitudinal studies provided evidence of a strong association between increased incidence of insulin resistance and T2DM in subjects with either low or high IGF-1 serum levels (200, 201)

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Therefore, monitoring serum GR activity holds potential clinical value for the auxiliary diagnosis and prognosis of these conditions [38]

Endothelial progenitor cells expressing CCR2 can be recruited from the circulation in response to tumor expression of CCL2, contributing to tumor angiogenesis [209]
