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Hyperinsulinemia and insulin resistance seem to be predominant features of PCOS, along with dysfunction of the hypothalamic-pituitary axis, which result in hormonal alterations, including increased serum luteinizing hormone (LH)/ follicle-stimulating hormone (FSH) ratio and circulating androgens

Odle et al., in 2014, reported how the l-isomer can be synthesized, and, consequently, high-purity dietary supplements are commercially available and are generally recognized as safe [14]

This delivery method addresses the critical issue of bioavailability

Importantly, GGT and insulin resistance were closely correlated [Figure 2]