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10.1034/j.1600-0447.2002.01300.x Acta Psychiatr
General Symptoms Dizziness or lightheadedness Paleness of skin and mucous membranes Gastrointestinal Symptoms Neurological Symptoms Numbness or tingling in hands and feet Difficulty walking Balance problems Memory loss or confusion Depression or mood changes Cardiovascular Symptoms Chest discomfort Increased risk of heart disease due to chronic anemia Complications of Untreated Pernicious Anemia If untreated, it can cause serious complications: Permanent nerve damage Cognitive impairment and dementia Increased risk of gastric cancer Heart failure due to prolonged anemia Early detection significantly reduces these risks
The rate of deamidation depends heavily on the neighboring amino acids
The half-IG exchange event occurs also for therapeutic IgG4 antibodies
