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Both in vitro and in vivo, the anti-inflammatory properties of 2-ME2 are partly mediated by the inhibition of macrophage activation [76]

Browne CA, Lucki I (2013) Antidepressant effects of ketamine: mechanisms underlying fast-acting novel antidepressants
& Liscum, L

Despite the known outcomes of the IVD degeneration cascade, the treatment of IVD degeneration is limited in that available conservative and surgical treatments do not reverse the pathology or restore the IVD tissue
