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Researchers should use appropriate laboratory tools and equipment to ensure accurate and sterile results

With the increase in RA severity degree, D3R-positive MCs in the synovial fluid are gradually reduced, led by ROS production, reduced antioxidant capacity, reduced cell membrane stability, and increased sensitivity of membrane components to a damaging agent, which are negatively correlated with the level of MDA and protein carbonylation (144)

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24 These guideline characteristics increase bias in: stakeholder involvement