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Lastly, it is essential to work with a healthcare provider to determine the best approach for maintaining optimal Glutathione levels

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Neuroactive Metabolites of the KP Among the metabolites produced in the KP, two are of particular interest: KYNA and QUIN, due to their pharmacodynamics and their respective neuroprotective and neurotoxic potentials [7,86]

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For instance, a study on rats with traumatic brain injury showed that administering glutathione reduced oxidative stress markers by 40%, improved mitochondrial function by 30%, and decreased neuronal death by 25%, compared to untreated controls [11]

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The FDA does not approve glutathione injectables for these uses, and the 2019 FDA warning flagged real safety concerns including contamination and allergic reactions

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