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LC-MS data were analyzed using the Xcalibur software (Thermo Fisher Scientific Inc.) for validating metabolites and retention times, TraceFinder 4.1 (Thermo Fisher Scientific Inc.) for automatic detection and quantification of peaks

These studies indicate that reduction of apoCIII by antisense oligonucleotide inhibition significantly reduces circulating triglyceride levels (654,655)

Unlike licensed medicines, they may also lack robust clinical evidence, agreed dosing standards, and systems to monitor side effects. Peptides are short chains of amino acids that play a role in regulating hormones, releasing neurotransmitters, and repairing tissue