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Combining -SG diet and PHGDHi is well-tolerated in vivo Our in vitro data indicated that the growth inhibitory response to serine and glycine depletion is greatly augmented by treatment of cells with the PHGDH inhibitor, prompting us to test the efficacy of this approach in vivo
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Studies reporting GSH levels in different blood components (plasma, serum, blood cells) were analyzed as sub-studies, with a total of 33 studies/sub-studies used for AD blood GSH analysis and 8 studies/sub-studies used for MCI blood GSH analysis

(1998) et confirmee par des travaux independants ulterieurs
