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Clearly, in humans, normal serum urate concentrations provide only a narrow safety window against potential deposition of urate crystals in the most susceptible tissue sites
76 In contrast, silencing and down-regulation of cellular BNIP3 levels by siRNA inhibited mitophagy, which led to an increasing ROS level and a decreased protein level of the antioxidant MnSOD
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Role of drug catabolism, modulation of oncogenic signaling and tumor microenvironment in microbe-mediated pancreatic cancer chemoresistance
