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Only one retrospective human clinical study has been published

It is the default pairing in recovery research the reasoning behind it is considered, not arbitrary

DSIP vs prescription sleep medications Benzodiazepines and Z-drugs (like Ambien) work by potentiating GABA receptors, producing sedation

doi: 10.1002/ajh.2830340208 10 Casella EB, Valente M, de Navarro JM, Kok F
