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Princen HM, Post SM, Twisk J

Robert Lustig, M.D., neuroendocrinologist, professor of pediatrics at the University of California, San Francisco (UCSF), and a bestselling author on nutrition and metabolic health

In support of the NRF2 pathway being a potential target for the treatment of ALS, studies have shown that NRF2 overexpression in astrocytes provided neuroprotection against mutated SOD1-induced toxicity and increased the median survival of mutant SOD1 transgenic mice (Vargas et al., 2008