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J Am Diet Assoc 98:10011008 Palheta MS, Graa JR, Santos AA et al (2014) The participation of the nitrergic pathway in increased rate of transitory relaxation of lower esophageal sphincter induced by rectal distension in dogs
Here is a detailed breakdown of what evidence-based protocols look like
Others are early in preclinical research but show extraordinary promise
References Center for Drug Evaluation and Research
