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Undoubtedly, the importance of homocysteine as a biological marker in health and disease is due to its significant position at the intersection of two distinct pathways: Firstly, the remethylation of homocysteine as part of the methionine cycle which is essential for methionine availability

These polyphenolic compounds, particularly chlorogenic acid and caffeic acid found abundantly in coffee, possess multiple hydroxyl groups that act as binding sites for iron molecules [1]

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