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EPI and cobalamin deficiency frequently occur together

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When you supplement methylfolate the body will clear a backlog of incomplete metabolic processes resulting in increased mobilisation and discharge of toxins and to avoid a healing reaction the 1 In addition to paving the way for detoxification you should use supplements to build up the other essential mineral and vitamin methyl donors (mentioned above) needed for complete methylation Sometimes its a good idea to start with phospholipids such as phosphatidylserine, phosphatidylcholine, pure choline et al, these provide a shortcut to supplying methyl groups to where they are needed compared to the long methylfolate metabolic path

Relation of serum ascorbic acid to serum vitamin B12, serum ferritin, and kidney stones in US adults