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Other studies have demostrated that individuals with OPRM1 A118G polymorphism respond correctly to treatment with naltrexone, these findings can determine that the response to a pharmacotherapy of the patient requires less dose of naltroxone to produce the expected therapeutical effect, avoiding toxicity related to high doses of treatment, including death in the worst cases ( Taqi et al ., 2019 )

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Lee et al., 2004

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Yeung H, Takeshita J, Mehta NN, Kimmel SE, Ogdie A, Margolis DJ,

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TRT and Heart Health: Does TRT REALLY Increase Heart Attack Risk

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