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Furthermore, melatonin supports neuronal survival by preserving mitochondrial function, which is essential for cellular energy metabolism and apoptosis regulation

On days 14 and 21 following experimental ischemic stroke, TWS119 treatment promoted microglial polarization by activating Wnt/-catenin signaling, which ultimately improved the local inflammatory microenvironment during the chronic phase of ischemic stroke

References Abdalrahman SS, Smail HO, Shallal AF
