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In the field of liver diseases, several studies tested the role of probiotics in liver cirrhosis, aiming at prevention of cirrhosis complications and infections, and reduction of systemic inflammation through the modulation of gut microbiota and intestinal permeability

Similarly, administration of epoxyeicosatrienoic acids (EETs) via the CYP2J2 pathway improves redox homeostasis in AEC2s, promotes Nrf2-dependent antioxidant responses, and indirectly stabilizes ER function by preserving phospholipid bilayer integrity (Zhang et al., 2023)

[DOI] [Google Scholar] Neufeld K

(PubMed) The FDA (USA) explicitly warned compounders about using dietary-supplement-grade glutathione to make sterile injectables, after documented adverse events linked to endotoxin contamination