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Resveratrol, Multiple Bioactivities for a Wide Range of Health BenefitsNew Innovative Extracts for Nutraceutical, Pharmaceutical, and Cosmetics Applications
In clinical settings, DFO has been shown to inhibit ferroptotic cardiomyocyte death, improving cardiac function in patients with iron overload, while DFX protects hepatocytes by preventing iron-driven ferroptosis (104106)
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Studies have demonstrated that the expression of GPX4 was significantly downregulated in vitiligo and that exogenous supplementation of GPX4 or iron chelators can alleviate melanocyte damage (55)
