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GSH reacts with ROS species and gets transformed to GSSG causing a decline in GSH/GSSG ratio that results in oxidative stress 10,11
This is confirmed by our previous publication, in which we observed baseline activation of the PERK-eIF2-ATF4-CHOP pathway proteins in the F35T compared to the 21T 11
These injections are administered in a clinical setting under provider oversight
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