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The case reports in this manuscript detail a series of patients who experienced distinct and potentially novel adverse reactions following the administration of tirzepatide, including palpitations, musculoskeletal pain, and headaches

Induction of heat shock proteins in B-cell exosomes

The resistance result from (i) reduced cellular drug accumulation, (ii) increased detoxification system, (iii) increased DNA repair process, (iv) decreased apoptosis, and (v) autophagy as summarized in Figure 2

Confusion can result in the classification of eicosanoids due to the use of the term group to define the origin of the various eicosanoids