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Effects of melanocortinson the behavior of ratsin thetest ofelevated cruciform maze and experimentally induced ofsocials

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Investigative Dermatology 143, S238

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The specific mechanism may be by activating VEGF-A / VEGFR1 -mediated AKT and p38/MAPK signaling pathways to upregulate downstream eNOS expression, which may increase the NO product synthesis thus promote angiogenesis of gastric mucosa, and also interact with ER stress

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