glutathione skin lightening clinical trial randomized The effects of the oral supplementation of L‐Cystine associated with reduced L‐Glutathione‐GSH on human pigmentation: a randomized, double‐blinded, benchmark‐ and placebo‐controlled - Duperray - 2022 PDF) Intravenous glutathione for skin
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Also, SOD2 is involved in tumorigenesis, proliferation, invasion, and metastasis in CCC (109)

For two consecutive weeks, mice were injected either with vehicle (PBS with 2% DMSO, 8.5% ethanol and 5% polyethylene glycol 400) and received normal drinking water or were injected with Auranofin (2.5 mg/kg) three times a week and received BSO (5 mM) in the drinking water ad libitum
10.1136/thoraxjnl-2020-216296 122 MaartensG.BrillM

Polyphenols modify Keap1 through covalent interactions or phosphorylation events, releasing Nrf2 from cytoplasmic sequestration (101, 102)
