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Description
While both flavonoids bind to unfolded GRP78 conformations, HNK exhibited a stronger affinity, leading to ER stress and cell death in various neuroectodermal tumor cell lines
Berberine treatment increases Akkermansia in the gut and improves high-fat diet-induced atherosclerosis in Apoe(-/-) mice
Metabolic changes included reduced indole, increased levels of in pipecolic acid, the methyl group donor SAM (S-Adenosylmethionine), and trigonelline (131)
PLoS ONE 8 , e74623 (2013)
