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medchemexpress glutathione peroxidase activator Tetrahydrobenzimidazole TMQ0153 targets OPA1 and restores drug sensitivity in AML via ROS-induced mitochondrial metabolic reprogramming | Journal of Experimental & Clinical Cancer Research Glutathione Peroxidase | MedChemExpress (MCE)

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Xinpeng He, Hongzhang Zhou, and Zhenyang Kong for their invaluable technical assistance with electron microscopy

medchemexpress glutathione peroxidase activator Tetrahydrobenzimidazole TMQ0153 targets OPA1 and restores drug sensitivity in AML via ROS-induced mitochondrial metabolic reprogramming | Journal of Experimental & Clinical Cancer Research Glutathione Peroxidase | MedChemExpress (MCE)

This reaction also requires input of one water molecule

medchemexpress glutathione peroxidase activator Tetrahydrobenzimidazole TMQ0153 targets OPA1 and restores drug sensitivity in AML via ROS-induced mitochondrial metabolic reprogramming | Journal of Experimental & Clinical Cancer Research Glutathione Peroxidase | MedChemExpress (MCE)

2019;20(13):pii: E3283

medchemexpress glutathione peroxidase activator Tetrahydrobenzimidazole TMQ0153 targets OPA1 and restores drug sensitivity in AML via ROS-induced mitochondrial metabolic reprogramming | Journal of Experimental & Clinical Cancer Research Glutathione Peroxidase | MedChemExpress (MCE)

IM, intermediate metabolizer

medchemexpress glutathione peroxidase activator Tetrahydrobenzimidazole TMQ0153 targets OPA1 and restores drug sensitivity in AML via ROS-induced mitochondrial metabolic reprogramming | Journal of Experimental & Clinical Cancer Research Glutathione Peroxidase | MedChemExpress (MCE)

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