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Arginase one could deplete circulating arginine, a substrate that is required by endothelial nitric oxide synthase (eNOS) for NO production (Stasch et al., 2011)
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Jorgensen JO, Jessen N, Pedersen SB, et al

Crocin ameliorates chronic obstructive pulmonary disease-induced depression via PI3K/Akt mediated suppression of inflammation

Riedelberger M., Penninger P., Tscherner M., Seifert M., Jenull S., Brunnhofer C., Scheidl B., Tsymala I., Bourgeois C., Petryshyn A., Glaser W., Limbeck A., Strobl B., Weiss G., Kuchler K., Cell Host Microbe 2020, 27, 454
