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Adverse events There was no statistically significant difference in the incidence of adverse events between treatment groups (Table 2)

One hundred fifty-three of 1027 metabolites assayed were significantly different based on disease status and 474 metabolites were nominally significant (Supplementary Table S1)

DEXA rats treated with MET or LCAR (300 or 500 mg/kg/day) demonstrated no significant difference in their serum total cholesterol levels relative to those of the DEXA group
