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Effectivecombinationtherapiesareurgentlyneededtotreattriple-negativebreastcancer(TNBC),whichisinsensitivetotheexistingtreatmentregimens.However,thesynergisticpotencyoftraditionalsmall-moleculecombinationsislimitedmainlyduetomismatchedmolarratios,inconsistentpharmacokinetics,andintratumoralaccumulationofindividualdrugs.Currentnanotechnologyoffersanunparalleleddevelopmentonadvancedcombinationdrugdelivery,especiallyratiometricdrugdeliveryinvivo.Recently,Prof.LIUXiangruiandProf.ZHOUTianhuafromtheZhe

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Abstract Redox-responsive colloidal mesoporous silica nanoparticles (CMS) drug delivery systems based on fluorescence resonance energy transfer (FRET) was successfully designed for targeting and real-time monitoring in potential cancer therapy

Explore Sygnature Discoverys comparison of LC-UV, LC-FLR, and LC-MS methods for detecting glutathione adducts in drug metabolism studies.