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Crizotinib, a class Ia small molecule dual inhibitor of c-MET and anaplastic lymphoma kinase (ALK) had been proposed for advanced non-small cell lung cancer therapy with activation of either c-ros oncogene 1 (ROS-1) or ALK [110]

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Doctors are likely to recommend a brief course of: Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen ( Motrin , Advil ) and naproxen ( Aleve ), which are available over the counter or in stronger prescription versions

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