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10.5534/wjmh.200085 22 ChoM

Effect of PTMS on phase separation IRD-containing ALS-associated proteins can be highly modified through PTMs because they are easily exposed to the external environment owing to a lack of secondary structure 41

Antioxidants play a key role here by stopping these byproducts from causing harm

Even in the absence of Ero1 activity in the mouse double knockout, PrxIV is able to use hydrogen peroxide produced by alternative mechanisms to drive disulfide formation
